Antibacterial Activity of Ethanolic Extract of <i>Matricaria chamomilla</i>, <i>Malva cylvestris</i>, and Capsella bursa-pastoris against Multidrug-Resistant <i>Pseudomonas aeruginosa</i> Strains

Background: This study aimed to determine antibacterial activity of ethanolic extract Matricaria chamomilla (chamomile), Malva sylvestris, and Capsella bursa-pastoris against multidrug-resistant (MDR) clinical isolates Pseudomonas aeruginosa. Methods: The plants were collected from Ziarat village Gorgan, Iran in April 2019. required parts the separated completely dried shade. After grinding, extraction was performed by maceration method. at 37°C for 24 hours. To obtain a concentration 50 mg/mL each extract, 500 mg plant dissolved 10 mL 5% dimethyl sulfoxide sterilized filtration through 0.45 µm membrane filter. For assay, agar well diffusion broth microdilution methods used. Results: Based on results, extracts M. sylvestris did not show any MDR P. aeruginosa both assays. No inhibitory effect observed chamomile method as well. In method, leaves showed minimum (MIC) bactericidal (MBC) determined 12.5 25 mg/mL, respectively. Conclusions: this study, isolates. Thus, it can be used production agents, is good option protection pathogenic microorganisms,